Initio's Side Effect fragrance is known for its rich, intoxicating, and sensual aroma. It combines notes of tobacco, vanilla, rum, and cinnamon with a warm, woody base. The fragrance is often described as having a spicy, sweet, and slightly boozy character, with a captivating and seductive quality. Some describe it as having a cherry-like vibe, reminiscent of amaretto or even cherry cough syrup, although cherry is not listed as an official note.